Trazodone is a prescription medication primarily used to treat depression and anxiety, but it’s also frequently prescribed off-label for insomnia. On forums like Reddit, users openly discuss their experiences with Trazodone—especially whether a 100mg dose of Trazodone can cause a “high.” But how much of this is fact, and how much is anecdotal? Let’s break it down.
What Is Trazodone?
Trazodone is classified as a serotonin antagonist and reuptake inhibitor (SARI). It works by altering the balance of serotonin in the brain, helping to improve mood and promote better sleep.
Common Uses of Trazodone
- Major depressive disorder (MDD)
- Generalized anxiety
- Insomnia (off-label)
- PTSD and chronic pain (in some cases)
Though it’s not considered a recreational drug, some Reddit threads explore whether higher doses, such as 100mg, can produce euphoric effects.
What Reddit Users Say About 100mg Trazodone
Reddit is a goldmine for firsthand experiences, and Trazodone is no exception. Here’s what users are commonly saying about the 100mg Trazodone experience:
1. “Can You Get High on 100mg Trazodone?”
Most Redditors agree: 100mg of Trazodone doesn’t produce a traditional “high”. Unlike drugs such as opioids or benzodiazepines, Trazodone lacks strong euphoric effects.
- User feedback often describes the effects as:
- Heavy sedation
- Grogginess or “zombie-like” feeling
- Mild disorientation
- Delayed motor skills or cognitive fog
Some users new to the drug may mistake these sedative effects for a “high,” but medically, it’s more accurate to call it central nervous system depression.
2. “What Happens After Taking 100mg?”
Many users take 100mg Trazodone at night to help with sleep and report:
- Falling asleep within 30–60 minutes
- Deep, extended sleep
- Residual drowsiness the next day
Redditors warn that taking it during the day may lead to extreme fatigue, making daily functioning nearly impossible.
Is 100mg of Trazodone a High Dose?
While 100mg may sound like a lot, it’s actually a moderate starting dose for many patients, especially those using it for depression. Here’s a quick breakdown:
- Low dose: 25–50mg (typically for insomnia)
- Moderate dose: 100–150mg
- High dose: 300–400mg+ (used in severe depression under supervision)
Reddit users note that individual tolerance varies, and what feels intense for one person may feel mild for another.
Trazodone Side Effects Discussed on Reddit
Side effects are a major topic on Reddit. Commonly mentioned issues include:
- Daytime drowsiness
- Dry mouth
- Dizziness
- Headaches
- Nausea
Unwanted “High” or Just Side Effects?
Some users report feeling “weird” or “disconnected” after taking Trazodone. These aren’t typical signs of being high—they’re usually side effects from the drug’s strong sedative action.
Important note: If these effects are overwhelming or long-lasting, Reddit users often suggest talking to a doctor for a dosage adjustment.
Dangers of Misusing Trazodone
Though Trazodone isn’t considered addictive, misusing it can still pose serious health risks. Some Redditors have shared cautionary tales about:
- Mixing Trazodone with alcohol or other depressants
- Taking higher-than-prescribed doses for sleep or anxiety
- Suddenly stopping the medication without tapering
These actions can lead to dangerous consequences like respiratory depression, serotonin syndrome, or severe withdrawal symptoms.
What Experts Say vs. Reddit Threads
Medical professionals emphasize that Trazodone should never be used to achieve a “high.” While Reddit provides valuable personal insights, medical advice should always come from a licensed healthcare provider.
Doctors highlight that:
- Trazodone is not a controlled substance and doesn’t cause classic euphoria.
- Effects felt at 100mg are usually therapeutic, not recreational.
- Long-term misuse can alter brain chemistry and lead to complications.
Is 100mg Trazodone Right for You?
If you’re considering or already taking 100mg of Trazodone, here are a few tips shared across Reddit and by healthcare providers:
Best Practices
- Take it at bedtime to avoid daytime drowsiness.
- Avoid alcohol or other sedatives.
- Be patient—some effects may take 1–2 weeks to stabilize.
- Talk to your doctor if you feel overly sedated or disconnected.
Conclusion: Trazodone at 100mg—Not a Recreational Drug
While Reddit is full of vivid stories and honest accounts, the overall consensus is that 100mg of Trazodone doesn’t cause a traditional “high.” Instead, most users experience sedation, grogginess, and deep sleep—which, though intense, aren’t euphoric.
If you’re exploring Trazodone for mental health or sleep, consult your doctor before adjusting your dose based on anecdotal Reddit advice.

Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.