When your dog is anxious, aggressive, or recovering from surgery, your vet might prescribe a medication like Trazodone to help. But if you’ve come across a 150 mg dose of Trazodone for your dog, you may have questions. Is it safe? What are the side effects? How should it be given?
This guide will walk you through everything you need to know about 150 mg Trazodone for dogs—from dosage and uses to risks and safety tips—so you can make informed decisions for your furry friend.
What Is Trazodone?
Trazodone is an antidepressant commonly used in human medicine to treat anxiety, depression, and insomnia. However, it’s also frequently prescribed off-label in veterinary medicine to help manage:
- Separation anxiety
- Noise phobias (e.g., fireworks or thunderstorms)
- Travel-related stress
- Post-operative recovery
- Aggression or reactivity
Trazodone works by increasing serotonin levels in the brain, promoting a calming effect without heavy sedation.
Is 150 mg of Trazodone Safe for Dogs?
🐾 It Depends on the Dog’s Weight and Condition
The safety and effectiveness of 150 mg of Trazodone depend on your dog’s:
- Weight
- Age
- Medical history
- Reason for use
💡 Typical canine Trazodone dosage ranges from 2.5 to 15 mg per kilogram (1.1 to 6.8 mg per pound) of body weight, given every 8 to 24 hours depending on the condition being treated.
For example:
- A 50-pound dog (about 22.7 kg) could be safely prescribed a 150 mg dose, falling within the appropriate dosage range.
- A smaller dog under 20 pounds would usually require a much smaller dose.
Always consult your veterinarian before giving Trazodone in any amount.
Common Uses of Trazodone in Dogs
1. Anxiety and Stress Relief
Trazodone is frequently used for:
- Dogs with generalized anxiety disorder
- Stress from vet visits or grooming
- Temporary anxiety (e.g., moving houses or new environments)
2. Post-Surgical Sedation
After surgery, vets often prescribe Trazodone to:
- Keep dogs calm and still during recovery
- Prevent injury by limiting activity
- Reduce pain-related stress
3. Behavioral Training Support
For dogs undergoing behavior modification, Trazodone can help:
- Lower reactivity
- Improve focus and cooperation
- Make desensitization training more effective
Side Effects of Trazodone in Dogs
While generally considered safe, Trazodone can cause side effects in some dogs, especially at higher doses like 150 mg.
⚠️ Common side effects include:
- Lethargy
- Gastrointestinal upset (vomiting, diarrhea)
- Panting or restlessness
- Dilated pupils
- Disorientation or uncoordinated movement
In rare cases, dogs may experience serotonin syndrome, a potentially life-threatening condition caused by excessive serotonin.
Watch for warning signs like:
- Tremors
- Rapid heart rate
- High body temperature
- Seizures
If you notice any of these symptoms, contact your vet immediately.
How to Safely Administer 150 mg Trazodone
💊 Tips for Proper Use:
- Always follow your vet’s prescription.
- Give the medication with food to reduce stomach upset.
- Monitor your dog’s behavior closely, especially after the first few doses.
- Avoid giving it alongside other serotonin-affecting drugs (like fluoxetine or tramadol) unless directed by your vet.
⏱️ How long does it take to work?
Trazodone usually takes effect within 1 to 2 hours after administration. Its calming effects may last up to 8 hours or more depending on the dog.
When to Avoid Trazodone
Do not give Trazodone if your dog has:
- A known allergy to the drug
- Heart, kidney, or liver problems
- Seizure disorders
- Is pregnant or nursing
Also, caution should be used in older dogs or those on multiple medications.
FAQs About 150 mg Trazodone in Dogs
✅ Can I split the tablet?
Yes, if prescribed by your vet, Trazodone tablets can be split for accurate dosing. Use a pill cutter for precision.
✅ Can I use human Trazodone?
Technically yes, but never give human medication without veterinary approval. Dosage and inactive ingredients may vary.
✅ How long can my dog stay on Trazodone?
Trazodone can be used short-term or long-term, depending on your vet’s guidance. Regular check-ins are recommended for dogs on chronic Trazodone therapy.
Final Thoughts: Talk to Your Vet First
150 mg Trazodone can be safe and effective for some dogs, especially larger breeds or those recovering from surgery. However, because dosage needs vary widely, professional veterinary guidance is essential to avoid complications.
When in doubt—always call your vet.
Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.