Is your dog dealing with anxiety, stress, or trouble sleeping? Trazodone, a commonly prescribed antidepressant for humans, is increasingly used in veterinary medicine to help dogs feel calm and comfortable. Understanding the right trazodone dosage for dogs is essential for safety and effectiveness, especially when dealing with a standard 50mg tablet.
In this article, we’ll break down everything you need to know about 50mg trazodone for dogs, including a dosage chart by weight, common uses, potential side effects, and tips for administering the medication safely.
What Is Trazodone and Why Is It Used for Dogs?
Trazodone is a serotonin antagonist and reuptake inhibitor (SARI) originally developed to treat depression and anxiety in humans. Vets commonly prescribe it to dogs for its calming and sedative effects.
Common Uses in Dogs:
- Anxiety and fear-based behaviors
- Separation anxiety
- Noise phobias (like thunderstorms or fireworks)
- Travel stress
- Post-surgical calming
Trazodone helps by balancing serotonin levels in the brain, which promotes relaxation without heavy sedation.
Is 50mg Trazodone Safe for Dogs?
Yes, 50mg trazodone is generally safe for dogs, but only when prescribed by a veterinarian. The correct dose depends heavily on your dog’s weight, overall health, and condition being treated. Giving too much trazodone can lead to side effects or even toxicity, so never self-prescribe.
Trazodone Dosage Chart for Dogs by Weight
The typical trazodone dosage for dogs ranges from 1.7 mg to 9 mg per pound of body weight, administered every 8 to 24 hours. Vets usually start at a lower dose and adjust based on the dog’s response.
Here’s a general dosage chart based on a 50mg tablet:
| Dog’s Weight (lbs) | Low Dose (mg) | High Dose (mg) | Approx. 50mg Tablets |
|---|---|---|---|
| 5 lbs | 8 mg | 45 mg | ⅙ to 1 tablet |
| 10 lbs | 17 mg | 90 mg | ⅓ to 2 tablets |
| 20 lbs | 34 mg | 180 mg | ¾ to 3.5 tablets |
| 30 lbs | 51 mg | 270 mg | 1 to 5.5 tablets |
| 40 lbs | 68 mg | 360 mg | 1.5 to 7 tablets |
| 50 lbs | 85 mg | 450 mg | 1.5 to 9 tablets |
| 60 lbs | 102 mg | 540 mg | 2 to 11 tablets |
| 70+ lbs | Varies | Consult Vet | Vet-guided dosing |
Note: These are general guidelines only. Always follow your vet’s instructions and start with the lowest effective dose.
How to Give Trazodone to Your Dog
Administering trazodone can be simple if done correctly:
- Hide it in a treat or soft food (like peanut butter or cheese)
- Use a pill pocket or crush the tablet (only if your vet approves)
- Give with food to reduce the risk of stomach upset
Dogs usually start to feel the calming effects within 30 to 60 minutes.
Possible Side Effects of Trazodone in Dogs
While most dogs tolerate trazodone well, side effects are possible—especially with high doses or interactions with other medications.
Common Side Effects:
- Sedation or drowsiness
- Upset stomach
- Panting or restlessness
- Lethargy
Serious Side Effects (Rare):
- Vomiting
- Agitation or hyperactivity
- Tremors or seizures
- Serotonin syndrome (a rare but dangerous condition)
Call your vet immediately if your dog shows any unusual symptoms after taking trazodone.
Important Safety Tips
To ensure your dog’s safety, keep these key precautions in mind:
- Consult your vet before starting trazodone
- Don’t exceed the recommended dose
- Watch for drug interactions, especially if your dog is on SSRIs or MAOIs
- Store trazodone out of reach of pets and children
Never give trazodone intended for humans without veterinary supervision.
When to Use Trazodone for Dogs
Trazodone can be a short-term solution for situational anxiety or a long-term management tool for ongoing behavioral issues.
Examples of when vets may recommend trazodone:
- Before a vet appointment or grooming visit
- During holidays with loud fireworks
- As a recovery aid after surgery
- In conjunction with behavioral training plans
Used properly, it can significantly improve your dog’s quality of life and emotional well-being.
Final Thoughts: Trazodone Can Help Your Dog Feel Calm and Safe
If your dog struggles with anxiety, trazodone may offer relief—but only when used correctly. Understanding the proper 50mg trazodone dosage for dogs by weight is essential to ensure safety and effectiveness.
Always consult your veterinarian before starting or adjusting trazodone for your dog. When used responsibly, trazodone can be a powerful tool to support a happier, more relaxed pup.
Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.