When people search for “1330 trazodone,” they’re often referring to a specific imprint found on a common prescription medication. Trazodone, known by its pill code “1330”, is frequently prescribed for treating depression, anxiety, and insomnia. But what exactly is trazodone, and what should patients know about this specific formulation?
In this guide, we’ll break down what 1330 trazodone is, its uses, benefits, side effects, and safe usage practices—all in an easy-to-understand format.
What Is 1330 Trazodone?
Trazodone 50 mg with the imprint “1330” is a prescription antidepressant most commonly used to treat major depressive disorder (MDD) and related conditions. It belongs to a class of medications called serotonin antagonist and reuptake inhibitors (SARIs).
Key Facts About 1330 Trazodone:
- Imprint: 1330
- Strength: 50 mg
- Color/Shape: White, round tablet
- Manufacturer: Zydus Pharmaceuticals
- Availability: Prescription only
- Drug Class: Phenylpiperazine antidepressants
Common Uses of Trazodone
Trazodone is a versatile medication that treats a range of conditions beyond depression. It’s particularly valued for its sedative effects, making it a dual-purpose drug.
Primary Uses:
- Major depressive disorder (MDD)
- Anxiety disorders
- Insomnia (off-label use)
- PTSD (Post-Traumatic Stress Disorder)
- Chronic pain management (in some cases)
Doctors often prescribe trazodone at lower doses for sleep issues and at higher doses for depression.
How 1330 Trazodone Works
Trazodone affects the brain’s chemical balance, specifically serotonin levels. It helps improve mood and emotional stability by:
- Inhibiting serotonin reuptake – keeping more serotonin available in the brain.
- Blocking certain serotonin receptors – reducing anxiety and agitation.
- Enhancing sleep quality – by promoting drowsiness without heavy sedation.
Recommended Dosage and Administration
The 50 mg 1330 trazodone tablet is often a starting dose for depression or a low dose for insomnia. However, dosage varies based on the condition being treated and patient factors.
General Guidelines:
- Depression: Start at 50–100 mg/day; can increase up to 400 mg/day (outpatient).
- Insomnia (off-label): Typically 25–50 mg at bedtime.
- Take with food to reduce side effects like dizziness or lightheadedness.
⚠️ Always follow your doctor’s instructions. Never adjust the dose without medical guidance.
Side Effects of 1330 Trazodone
Like all medications, trazodone may cause side effects, though not everyone experiences them. Understanding possible reactions can help you manage expectations and know when to seek help.
Common Side Effects:
- Drowsiness
- Dizziness
- Dry mouth
- Blurred vision
- Constipation
Serious (but rare) Side Effects:
- Priapism (painful, prolonged erection)
- Serotonin syndrome
- Irregular heartbeat
- Low blood pressure
If you experience chest pain, fainting, or severe mood changes, contact a doctor immediately.
Drug Interactions to Watch Out For
Trazodone can interact with many medications, increasing the risk of side effects or serotonin syndrome.
Avoid mixing trazodone with:
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- Other antidepressants (without medical oversight)
- Alcohol or sedatives – can worsen drowsiness
- Certain antifungal or antibiotic medications
Tell your doctor about all medications and supplements you’re taking.
Safety Tips and Precautions
To use 1330 trazodone safely, follow these essential guidelines:
- Start with the lowest effective dose
- Avoid driving or operating machinery until you know how it affects you
- Do not stop suddenly – taper under doctor supervision
- Inform your doctor if you’re pregnant, breastfeeding, or have liver/kidney problems
FAQs About 1330 Trazodone
Is 1330 trazodone a sleeping pill?
Not technically. While not FDA-approved as a sleep aid, it’s commonly prescribed off-label for insomnia due to its sedative effects.
How long does it take for trazodone to work?
- For sleep: Effects may be noticeable within 1–2 hours.
- For depression: May take 2–4 weeks for full benefits.
Can I get addicted to trazodone?
Trazodone has a low risk of addiction, especially compared to traditional sleep aids or benzodiazepines.
Conclusion: Is 1330 Trazodone Right for You?
Trazodone with the 1330 imprint is a trusted medication for managing depression, anxiety, and sleep disorders. While generally safe and effective, it should be used under medical supervision, with attention to side effects, interactions, and correct dosage.
If you’re considering trazodone for sleep or mental health support, consult your healthcare provider for personalized guidance.

Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.