If you’re exploring options for Trazodone 100mg, chances are you’re navigating the intersection of mental health treatment and budget management. Trazodone is a commonly prescribed medication for depression and insomnia, and its affordability makes it an attractive option for many.
But what exactly is the cost of 100mg Trazodone, and how can you get the best deal? In this guide, we’ll break it down for you—covering everything from retail prices and insurance coverage to generic options and savings tips.
What Is Trazodone and What Is It Used For?
Trazodone is an FDA-approved antidepressant primarily used to treat major depressive disorder. However, it’s also widely prescribed off-label for:
- Insomnia
- Anxiety disorders
- PTSD
- Chronic pain
It belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs) and works by restoring the balance of serotonin in the brain, helping improve mood and sleep.
Why Focus on the 100mg Dosage?
While Trazodone comes in several strengths—50mg, 100mg, 150mg, and 300mg—the 100mg dose is among the most commonly prescribed. It’s often used:
- As a starting dose for depression
- For sleep disturbances, usually taken before bed
- In combination therapy for anxiety and mood disorders
Because of its versatility, 100mg Trazodone is widely available, making pricing and cost comparisons especially relevant.
Average Cost of 100mg Trazodone (Without Insurance)
Prices for 100mg Trazodone can vary significantly depending on where you buy it. Here’s a quick breakdown of the average retail prices in the U.S. (as of early 2025):
Quantity | Average Price (Retail) |
---|---|
30 tablets | $10 – $25 |
90 tablets | $20 – $50 |
180 tablets | $40 – $90 |
💡 Tip: Buying in bulk often results in a lower per-tablet cost.
These prices are for generic Trazodone, which is chemically identical to the brand name but significantly cheaper.
How Insurance Affects the Price
If you have health insurance, the out-of-pocket cost for Trazodone may be much lower—or even free. Coverage varies depending on:
- Your insurance provider
- Your copay plan
- Whether you use an in-network pharmacy
Medicare and Medicaid also cover Trazodone under most prescription plans. Be sure to check your formulary list to confirm.
Generic vs. Brand Name: What’s the Difference in Price?
Trazodone’s brand name is Desyrel, but this version is rarely prescribed today due to its higher cost and the availability of generics.
Type | Typical Cost |
---|---|
Brand Name | $100+ per month |
Generic | $10–$30 per month |
Unless specifically required by your doctor, there’s usually no clinical advantage to paying more for the brand name.
Where to Buy Trazodone for Less
1. Local Pharmacies
Most chain pharmacies like CVS, Walgreens, and Rite Aid carry Trazodone, but prices can vary. It’s worth calling ahead or checking their websites for pricing.
2. Online Pharmacies
Online platforms like:
- GoodRx
- Blink Health
- SingleCare
allow you to compare prices and use discount coupons, often cutting your cost by 50% or more.
3. Big-Box Retailers
Stores like Walmart, Costco, and Kroger offer low-cost generic drug programs, where Trazodone might be as little as $4 for 30 tablets.
✅ Pro Tip: You don’t need a membership at Costco to use their pharmacy!
Can You Save More With Prescription Discount Cards?
Yes! Prescription savings cards can dramatically reduce your costs, especially if you’re paying out of pocket. Popular options include:
- GoodRx Gold
- RxSaver
- WellRx
These cards are free and can be used even without insurance. Simply present the card or digital code at the pharmacy for instant savings.
Are There Any Hidden Costs?
While the medication itself is generally inexpensive, here are a few additional costs to keep in mind:
- Doctor visits (to get a prescription)
- Follow-up appointments
- Lab tests (sometimes required to monitor side effects)
Still, Trazodone remains one of the most cost-effective medications in its class.
Conclusion: Affordable Relief Is Within Reach
Trazodone 100mg is not just effective—it’s also very affordable compared to other antidepressants and sleep aids. Whether you’re paying out of pocket or using insurance, there are plenty of ways to save.
To recap:
- Expect to pay $10–$30/month for generic Trazodone without insurance.
- Use online tools and discount cards to lower your price.
- Consider buying in bulk and comparing pharmacy prices.

Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.