Introduction
Trazodone is a widely prescribed medication used to treat depression, anxiety disorders, and insomnia. It belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), helping to balance brain chemicals that regulate mood and sleep.
But how much trazodone should you take? Understanding the correct dosage is crucial for safety and effectiveness. In this article, we’ll explore the proper dosing guidelines, factors influencing dosage, and what to expect when taking trazodone.
What Is Trazodone Used For?
Trazodone is primarily prescribed for:
- Depression – It helps restore serotonin balance, improving mood and emotional stability.
- Anxiety disorders – It reduces excessive worry and nervousness.
- Insomnia – Many doctors prescribe it off-label for sleep issues due to its sedative properties.
- Chronic pain management – Sometimes used as part of a treatment plan for pain conditions like fibromyalgia.
Recommended Dosages of Trazodone
Trazodone dosage varies based on the condition being treated, the patient’s age, and overall health. Below are the general dosing guidelines:
Trazodone for Depression
- Starting dose: 150 mg per day, divided into multiple doses.
- Maintenance dose: 300–400 mg per day (may vary based on response).
- Maximum dose: 600 mg per day (for inpatients under medical supervision).
- Administration: Best taken with food to enhance absorption and reduce side effects.
Trazodone for Insomnia (Off-label Use)
- Starting dose: 25–50 mg before bedtime.
- Common effective dose: 50–100 mg.
- Maximum dose: Usually not exceeding 200 mg per night.
- Administration: Take 30 minutes before sleep to allow time for drowsiness to set in.
Trazodone for Anxiety
- Starting dose: 75–150 mg per day.
- Common effective dose: 200–300 mg per day, divided into doses.
- Administration: Often taken with food to minimize nausea.
Factors That Affect Trazodone Dosage
Several factors influence the optimal trazodone dose for each individual, including:
- Age – Older adults may require lower doses due to slower metabolism.
- Medical conditions – Liver or kidney impairments may necessitate dosage adjustments.
- Other medications – Certain drugs can interact with trazodone, affecting its effectiveness.
- Individual response – Some patients require higher or lower doses depending on how their body metabolizes the drug.
Potential Side Effects of Trazodone
Like all medications, trazodone comes with potential side effects. Some of the most common include:
Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth
- Nausea
- Blurred vision
Serious Side Effects (Seek Medical Help Immediately)
- Irregular heartbeat or chest pain
- Severe dizziness or fainting
- Shortness of breath
- Priapism (painful, prolonged erection in men)
- Serotonin syndrome (agitation, hallucinations, rapid heartbeat, excessive sweating)
How to Take Trazodone Safely
To maximize the benefits and minimize risks, follow these best practices:
- Take trazodone exactly as prescribed by your doctor.
- Avoid alcohol while using trazodone, as it can enhance drowsiness and dizziness.
- Do not suddenly stop taking the medication—this can cause withdrawal symptoms like irritability, anxiety, and sleep disturbances.
- Monitor for side effects and report any severe reactions to your healthcare provider.
Frequently Asked Questions
Can You Overdose on Trazodone?
Yes, taking excessive trazodone can lead to overdose symptoms such as extreme drowsiness, seizures, or respiratory distress. If you suspect an overdose, seek medical attention immediately.
How Long Does Trazodone Take to Work?
- For insomnia, effects are usually felt within 30–60 minutes after taking it.
- For depression and anxiety, it may take 1–2 weeks to notice improvement, with full effects developing over 4–6 weeks.
Is Trazodone Addictive?
Trazodone is not considered addictive, but discontinuing it suddenly can lead to withdrawal symptoms. Always taper off under a doctor’s guidance.
Conclusion
Trazodone is a versatile medication used for depression, anxiety, and sleep disorders. Understanding the correct dosage is essential for safety and effectiveness. Always consult your doctor to determine the best dose for your specific needs.
If you found this guide helpful, consider sharing it with others who might benefit. And if you have any questions, don’t hesitate to reach out to a healthcare professional for personalized advice.

Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.