Introduction
Trazodone is a widely used antidepressant that has been in the market for decades. While many recognize it as a generic medication, it is also available under various brand names. Understanding these brand names, their differences, and how trazodone is prescribed can help patients make informed decisions about their mental health treatment. In this article, we’ll explore the brand names of trazodone, its uses, benefits, and potential side effects.
What Is Trazodone?
Trazodone is a medication primarily prescribed for depression and anxiety disorders. It belongs to the class of serotonin antagonist and reuptake inhibitors (SARIs), helping to balance serotonin levels in the brain. Additionally, it is often used off-label for insomnia due to its sedative effects.
Key Uses of Trazodone
- Treating major depressive disorder (MDD)
- Managing anxiety disorders
- Helping with sleep disorders (off-label use)
- Reducing symptoms of fibromyalgia (off-label use)
Popular Brand Names of Trazodone
Although trazodone is commonly available in its generic form, it has been marketed under several brand names. Some of the most notable ones include:
1. Desyrel
One of the most well-known brand names, Desyrel, was widely prescribed for depression and anxiety. However, in many regions, Desyrel has been discontinued, and most patients now rely on generic trazodone.
2. Oleptro
Oleptro is an extended-release formulation of trazodone. Unlike standard trazodone, which requires multiple doses per day, Oleptro offers a sustained effect, making it more convenient for individuals who need continuous symptom relief.
3. Trittico (Available in Some Countries)
In certain countries, trazodone is sold under the brand name Trittico, which comes in controlled-release tablets. This formulation may help minimize side effects such as drowsiness while still maintaining efficacy.
Generic vs. Brand Name Trazodone: What’s the Difference?
Effectiveness
Both generic and brand-name trazodone contain the same active ingredient and are equally effective in treating depression and related conditions.
Price Differences
- Generic trazodone is often more affordable than brand-name versions, making it the preferred choice for most patients.
- Brand-name medications may have specialized formulations (like extended-release), which can justify a higher cost.
Availability
- Generic trazodone is widely available in most pharmacies.
- Brand-name versions like Oleptro are less common and may require special prescriptions or orders.
Common Side Effects of Trazodone
While trazodone is generally well-tolerated, some users may experience side effects. Common ones include:
- Drowsiness
- Dizziness
- Dry mouth
- Nausea
- Blurred vision
Rare but Serious Side Effects
- Serotonin syndrome (from excessive serotonin levels)
- Heart rhythm abnormalities
- Severe allergic reactions
How to Take Trazodone Safely
To maximize the benefits of trazodone while minimizing risks, follow these tips:
- Take it exactly as prescribed by your doctor.
- Avoid alcohol and other central nervous system depressants.
- Be cautious when driving or operating machinery, as drowsiness is common.
- If using it for sleep, take it 30 minutes before bedtime.
- Do not suddenly stop taking trazodone without consulting a healthcare provider.
Conclusion
Trazodone is a versatile medication available in both generic and brand-name versions, including Desyrel, Oleptro, and Trittico. While the generic version is widely used due to affordability, brand-name options may offer extended-release benefits for certain patients. If you’re considering trazodone for depression, anxiety, or sleep disorders, consult your doctor to determine the best formulation for your needs.
Looking for more information on trazodone and its alternatives? Speak to a healthcare provider today to explore the best treatment options for you!

Abraham Finley is a health writer passionate about providing clear, reliable information on Trazodone and mental health. He created TrazodoneSUC.com to help readers make informed decisions about their well-being.